Please note that our colleagues living in China will join us online and that posters will be printed and posted in Toulouse during the two poster sessions. 

Wednesday, 14 September 2022 - Library hall, (N°8 on the map)

17:00 - 19:00       Registration in the library Hall

18.00 – 20.00      Welcome reception around the posters - Poster Session 1 in the library hall 

Thursday, 15 September 2022 - Vinci amphitheater, (N° 20 on the map)

09:00 – 09:10      Welcome address

Plenary Talks: Physiology and Systems Biology (Chair Lee Lynd) 

09:10 – 09:50       Isabelle Meynial-Salles
Molecular characterization of the missing electron pathways for butanol synthesis in Clostridium acetobutylicum

09:50 – 10:30       Henri-Pierre Fiérobe 
How the catabolism of a complex polysaccharide reveals an unconventional central carbon metabolism in Ruminiclostridum cellulolyticum.

10:30 – 11:00      Coffee break - amphi 05

 Short Talks : Physiology and Systems Biology (Chair Peter Dürre)

11:00 – 11:25       Daniel Olson
A metabolic mechanism for the extreme ethanol sensitivity of Clostridium thermocellum

11:25 – 11:50       Jeroen Koendjbiharie
Functional Analysis of H+-Pumping Membrane-Bound Pyrophosphatase, ADP-Glucose Synthase, and Pyruvate Phosphate Dikinase as Pyrophosphate Sources in Clostridium thermocellum

11:50 – 12:15      Ya-Jun Liu  (ONLINE)
Deciphering cellodextrin and glucose uptake in Clostridium thermocellum

12:30 – 13:30      Lunch break - INSA restaurant, lunch room (N° 8 on the map)

Short Talks :   Physiology and Systems Biology (Chair Klaus Winzer)

13:30 – 13:55      Ziyong Liu  (ONLINE)
Role of short chain fatty acids reuse pathway on alcohol production during fermentation in Clostridia

13:55 – 14:20      Karan Kumar  (ONLINE)
Deciphering the physiological underpinning of solventogenesis in Clostridia using genome-scale metabolic models

14:20 – 14:45      Saskia Baur
Solvent formation and sol mRNA expression in Clostridium saccharoperbutylacetonicum affected by the long non-coding RNA Assolrna

14:45 – 15:10      François Wasels
Investigating Carbon Catabolite Repression in Clostridium acetobutylicum

15:10 – 15:30      Coffee break -amphi 05

Short Talks : Physiology and Systems Biology  (Chair Peter Dürre)

15:30 – 15:55      Cong Ren  (ONLINE)
Seeking, isolating and revealing metabolic characteristics of novel hexanoate-producing bacteria in the class Clostridia

15:55 – 16:20      Benjamin Woolston
Investigating the metabolic flexibility of the methanol-consuming acetogen Eubacterium limosum

16:20 – 16:45     Guillaume Pregnon
A global systems biology approach to characterize the metabolism of Eubacterium limosum B2

16:45 – 17:10     Kaspar Valgepea
Testing the limits of acetogen metabolism

17:10 – 19:10      Poster Session 2 and Whisky tasting - Library hall, (N° 8 on the map)

20:00 – 22:00      Dinner - at the CHELALA,  9 Rue du rempart Villeneuve, Toulouse city center - metro line B stop Jean Jaures station

  Friday, 16 September 2022 Vinci amphitheater, (N° 20 on the map)

Plenary Talks: Genetics and Synthetic Biology (Terry Papoutsakis)

09:00 – 09:40       David Jones  (ONLINE)
Solvent -producing clostridia revisited.

09:40 – 10:20      Nigel Minton
Engineering Biology Tools for Anaerobes: from Clostridium I to XVI

10:20 – 10:40      Coffee break - room amphi 05

 Short Talks : Genetics and Synthetic Biology (Chair Wolfgang Liebl)

10:40 – 11:05      Jie Zhang  (ONLINE)
Exploiting heterologous and endogenous CRISPR-Cas systems for genome editing in the probiotic Clostridium butyricum

11:05 – 11:30      Maximilian Flaiz
Novel approaches to light-up solventogenic and acetogenic Clostridia the FAST way

11:30 – 11:55      Martina Schneider
Overcoming restriction barriers in the secondary fermenter Clostridium kluyveri

11:55 – 12:20     Aleksandra Kubiak
Improved Genome Editing and Gene Expression Control in Clostridia: Rationally Designed Gene Regulation for Industrial and Medical Applications

12:30 – 13:30      Lunch break -  INSA restaurant, lunch room (N° 8 on the map)

Plenary Talks :   Metabolic Engineering (Chair Isabelle Meynial Salles)

13:30 – 14:10     Peter Dürre
The genus Clostridium: its importance and exploitation from ancient times to these days

14:10 – 14:50     Terry Papoutsakis
Production of Chemicals from Mixotrophic Clostridium Cocultures Enabling CO₂ Fixation to Achieve Transformative Product Yields

Short Talks : Metabolic Engineering (Chair Benjamin Woolston)

14:50 – 15:15      Xin Fengxue  (ONLINE)
Construction of "necklace pattern" microbial consortium for the de novo synthesis of butyl butyrate from renewable resources

15:15 – 15:40      Yi Wang
Engineer Clostridium for renewable fatty acid ester production

15:40 – 16:00      Coffee break - room amphi 05

16:00 – 16:25     Minyeong Yoo
A synthetic biology approach for the stable and continuous production of advanced biofuels by Clostridium acetobutylicum

16:25 – 16:50          Shivani Garg 
Engineering Gas Fermenting Clostridia For CarbonSmart Biomanufacturing

16:50 – 17:15     Frank R. Bengelsdorf
Autotrophic lactate production from H₂ + CO₂ using recombinant and fluorescent FAST‑tagged Acetobacterium woodii strains

17:15 – 17:40     Luc Lenglet
Expedite metabolic engineering of anerobes with FAST from The Twinkle Factory

17H40 Departure by bus from the INSA entrance for the visit of the Aeroscopia Museum and the dinner.
Return by bus with a drop off in downtown Toulouse and at INSA

17:40 – 20:00       Social program: private visit of the Aeroscopia Museum

20:00-22:00         Conference Dinner within the Aeroscopia Museum

Saturday, 17 September 2022- Vinci amphitheater, (N° 20 on the map)

Plenary Talks: Feedstock utilization, industrial and new applications (Chair Ana M. Lopez-Contreras )

09:00 – 09:40       Evert Holwerda
New Insights into Lignocellulose Deconstruction by Defined Cultures and Mixed Consortia.

09:40 – 10:20       Tom Wilding-Steele
The Weizmann process revisited for lignocellulosic biofuels production

10:20 – 10:40      Coffee break - room amphi 05

 Short Talks : Feedstock utilization, industrial and new applications (Chair Daniel Olson)

10:40 – 11:05       Lee Lynd
A Strategic Perspective on Using Clostridia and Lignocellulose-Fermenting Anaerobes to Address the Climate Challenge.

11:05 – 11:30        Ana M. Lopez-Contreras
Macroalgae as substrate for fermentation by solventogenic Clostridia

11:30 – 11:55        Peter Götz
From Metabolic Modeling to Design and Start-up of a Pilot Plant for Biosolvent Production

11:55 – 12:20        Martin Tangney
From Innovation to Industry – Celtic Renewables 

12:30 – 13:30      Lunch break -  INSA restaurant, lunch room (N° 8 on the map)

Short Talks : Feedstock utilization, industrial and new applications (Chair Daniel Olson)

13:30 - 13:55         Bryan Tracy
Postbiotic Protein and Fatty Acids – Clostridium based solutions to sustainable nutrition and biochemicals        

13:55 - 14:20        Sara Benito-Vaquerizo
Model-driven approach led to a novel co-culture of Clostridium autoethanogenum and Clostridium beijerinckii for the conversion of CO₂/H₂ and lactic acid into carboxylic acids

14:20 – 14:45         Alexander Mook
Synthetic co-cultivation of A. woodii and C. drakei for production of medium-chain organic acids from H₂ and CO₂

14:45 – 15:10         Diana Sousa
Clostridia Mix & Match - Synthetic co-cultures to convert CO to carboxylic acids

15:10– 15:30         Conclusions and introduction of the next conference

15:30 – 16:00      Coffee break and end of the conference - amphi 05